If you have narrow drainage angles or you have long-term (chronic) closed-angle glaucoma, you may need to avoid medicines that widen (dilate) the pupil, the dark spot in the center of the eye. Having wide pupils when you have these other problems may cause acute closed-angle glaucoma. This is a dangerous condition that requires medical care right away to prevent lasting damage to your eye.
Some examples of prescription and over-the-counter medicines that may dilate the pupils are:
Antihistamines and decongestants
Motion sickness medicines
Some medicines used to treat depression (tricyclic antidepressants)
Talk with your eye specialist about medicines that you should not take.
Medical Review:Adam Husney MD - Family Medicine & Christopher J. Rudnisky MD, MPH, FRCSC - Ophthalmology