finasteride and tadalafil

Pronunciation: fin AS ter ide and ta DA la fil

What is the most important information I should know about finasteride and tadalafil?

Taking finasteride and tadalafil with certain other medicines can cause a sudden and serious decrease in blood pressure.

Do not take finasteride and tadalafil if you also use riociguat, or a nitrate drug such as nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, or recreational drugs such as "poppers."

Get medical help at once if you have nausea, chest pain, or dizziness during sex.

What is finasteride and tadalafil?

Finasteride and tadalafil is used to treat symptoms of benign prostatic hyperplasia (BPH) in men.

This medicine is for use in men only.

Finasteride and tadalafil may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking finasteride and tadalafil?

You should not use finasteride and tadalafil if you are allergic to it, or if you take:

  • other medicines to treat pulmonary arterial hypertension, such as riociguat.

Do not take finasteride and tadalafil if you are also using a nitrate drug for chest pain or heart problems. These include nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate, butyl nitrate or nitrite ("poppers"). Taking finasteride and tadalafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

Finasteride and tadalafil is not for use in women.

Tell your doctor if you have ever had:

  • heart problems (chest pain, a heart rhythm disorder, heart failure);
  • pulmonary hypertension;
  • a heart attack or stroke;
  • high or low blood pressure;
  • liver disease;
  • kidney disease (or if you are on dialysis);
  • retinitis pigmentosa (an inherited condition of the eye);
  • vision problems;
  • hearing problems;
  • bleeding problems;
  • a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
  • a physical deformity of the penis (such as Peyronie's disease), or an erection lasting longer than 4 hours; or
  • a stomach ulcer.

Do not use finasteride and tadalafil during pregnancy. This medcine can cause birth defects if a woman is exposed to it during pregnancy. A crushed or open capsules of this medicine should not be handled by a woman who is pregnant or may become pregnant. The medicine from a broken capsule could be absorbed through the skin.

How should I take finasteride and tadalafil?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take one finasteride and tadalafil capsule every day without food at about the same time for up to 26 weeks.

Do not take finasteride and tadalafil more than one time each day.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using finasteride and tadalafil.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can. Do not take more than one dose per day.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking finasteride and tadalafil?

Drinking alcohol with this medicine can cause side effects.

What are the possible side effects of finasteride and tadalafil?

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Call your doctor at once if you have:

  • heart attack symptoms --chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
  • an erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis); or
  • a lump or pain in your breast, or nipple discharge.

Stop using finasteride and tadalafil and call your doctor at once if you have:

  • ringing in your ears or sudden hearing loss; or
  • vision changes or sudden vision loss.

Common side effects may include:

  • headache;
  • indigestion;
  • back pain, muscle aches,
  • loss of interest in sex, impotence, difficulty having an orgasm;
  • enlarged or painful breasts;
  • stuffy or runny nose; or
  • flushing (sudden warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect finasteride and tadalafil?

Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

Tell your doctor about all your current medicines. Many drugs can affect finasteride and tadalafil, especially:

  • medicines to treat erectile dysfunction or pulmonary arterial hypertension;
  • drugs to treat high blood pressure or a prostate disorder;
  • an antibiotic such as clarithromycin, erythromycin, rifampin, or telithromycin;
  • antifungal medicine such as ketoconazole or itraconazole; or
  • medicine to treat HIV/AIDS, such as ritonavir and others.

This list is not complete and many other drugs may affect finasteride and tadalafil. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your doctor or pharmacist can provide more information about finasteride and tadalafil.

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