University of Michigan Health C.S. Mott Children's Hospital is the largest pediatric blood and marrow transplant (BMT) program in the state of Michigan, with recognized expertise in established transplant techniques and innovative research initiatives.
We currently perform 50-60 transplants annually for a wide array of pediatric cancers (such as leukemias, lymphomas, brain tumors and neuroblastoma), immune system disorders, hemoglobin disorders (sickle cell disease, thalassemia), metabolic disorders, and other rare blood cell disorders.
We offer both autologous (obtained from the same individual) and allogeneic (obtained from a donor) transplants to our patients. The type of transplant you receive depends upon your primary condition. Patients receiving autologous transplants will undergo collection and subsequent infusion of their own stem cells. Patients receiving allogeneic transplants will receive stem cells from a living donor, either a relative or donor identified from the one of the worldwide bone marrow or cord blood registries.
Why choose Mott for bone and marrow transplant?
Patients at Mott have access to the latest transplant techniques and procedures.
- We are one of 20 core sites within the Blood and Marrow Transplant Clinical Trials Network (BMT CTN), a cooperative group of leading transplant centers in North America. The BMT CTN specializes in developing “cutting edge” clinical trials for children and adults undergoing transplant.
- We are one of 18 pediatric centers in North America with the capability to deliver MIBG therapy to patients with advanced neuroblastoma, having developed the technology at our center over 40 years ago.
- Our BMT faculty had served in leadership roles for national trials performed within the BMT CTN, the Children’s Oncology Groupv (COG), and the Pediatric Transplant and Cellular Therapy Consortium (PTCTC).
- We have developed a national reputation for our work in preventing and treating graft versus host disease (GVHD) following allogeneic transplant, with GVHD being one of the most serious complications that can affect transplant recipients.
- Our program has been accredited by the Foundation for the Accreditation of Cellular Therapy (FACT) since 2001, one of the initial transplant centers to receive this national accreditation.
We have a dedicated multidisciplinary team, consisting of pediatric-trained physicians, nurse practitioners, nurses, pharmacists, nutritionists, social workers, and child life specialists, all dedicated specifically to the care of your child during transplant. Each member of our team is committed to working closely with children and their families to help them fully understand their care plan and the BMT treatment process. Our mission is to not only provide state-of-the-art care for the patients of today, but to identify novel therapy options for the patients of tomorrow.
Which conditions benefit from bone and marrow transplant?
Blood and marrow transplant can be an effective treatment option for a number of blood disorders and cancers, including:
- Leukemia
- Lymphoma
- Immunodeficiencies
- Bone marrow failure syndromes
- Lymphoproliferative diseases
- Neutrophil disorders
- Neuroblastoma
- Wilm's tumor
- Brain tumors
- Retinoblastoma
- Sickle cell disease
- Thalassemia
- Inborn errors of metabolism
C.S. Mott Children's Hospital is proud to be:
- A member of the National Marrow Donor Program.
- An active participant in the Children's Oncology Group, whose mission is to cure and prevent childhood cancer through scientific discovery and compassionate care.
- Ranked among the nation’s top pediatric cancer programs by U.S. News & World Report
Next steps
Make an Appointment with Pediatric Bone and Marrow Transplant.
For adult patients, visit our Adult Blood and Marrow Transplant online.