James Albert Connelly MD

Assistant Professor, Pediatrics
Pediatric Hematology/Oncology, Pediatrics

Video profile


U of M Pediatric Hematology Oncology

C.S. Mott Children's Hospital Floor 7
1540 E Hospital Dr SPC 4257
Ann Arbor


Medical School or Training

  • Washington University School of Medicine, 2003


  • University of Michigan Health System, Pediatrics, MI, 2006


  • Pediatric Hematology/Oncology, University of Michigan Health System, 2009

Professional Organizations

  • American Society of Pediatric Hematology and Oncology

  • Children's Oncology Group

  • Pediatric Blood and Marrow Transplant Consortium

Board Certification

  • Pediatrics

  • Pediatric Hematology-Oncology


Dr. Connelly's clinical and research interests focus on transplant for non-malignant diseases and detecting and preventing long-term consequences of cancer and transplant therapy.  He is a member of national research teams to improve transplant outcomes in patient with sickle cell, thalassemia, and immune deficiencies.  Dr. Connelly also studies how to optimize the health status of BMT survivors. He is conducting research with the goal of developing strategies to avoid or overcome cardiac and neurocognitive complications in children who undergo BMT.

Recent Publications:

  1. Caslini C, Connelly JA, Serna A, Broccoli D, Hess JL. MLL associates with telomeres and regulates telomeric repeat-containing RNA transcription. Mol Cell Biol, 29: 4519-26, 2009.
  2. Muntean A, Tan J, Sitwala K, Yongsheng H, Bronstein J, Connelly JA, Venkatesha B, Elenitoba-Johnson K, Hess JL. The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis. Cancer Cell, 17:609-21, 2010.
  3. Connelly JA, Choi SW, Levine JE. Hematopoietic stem cell transplantation for severe congenital neutropenia. Curr Opin Hematol, 19:44-51, 2012. 


Dr. Connelly received his medical training at Washington University in St. Louis.  He received both his pediatric general and hematology/oncology training at the University of Michigan.  He has continued on as faculty at the University of Michigan and now serves in two leadership positions. He is the Associate Director of the Immuno-Hematology Comprehensive Program whose goal is to treat and research patients with disorders of the immunologic and hematologic systems.  He is also the Director of the Pediatric Bone Marrow Transplant Late Effects program. Outside of work he spends his time with his family including raising two beautiful girls.