Medical School or Training
Wayne State University School of Medicine, 1999
New York University - Bellevue Medical Center, Pediatrics, NY, 2002
Pediatric Hematology/Oncology & Bone Marrow Transplant, University of Michigan Health System, 2005
American Society of Hematology
American Association for Cancer Research
Central Society for Clinical Research
Dr. Choi’s research focus is in the prevention and treatment of graft versus host disease (GVHD), the major complication of allogeneic hematopoietic cell transplantation (HCT). With her collaborator in the Adult Blood and Marrow Transplantation Program, Dr. Pavan Reddy, she has taken laboratory insights demonstrating the role of histone deacetylase inhibition in GVHD, to conduct a novel clinical trial of GVHD prevention using the anti-cancer drug, vorinostat. This work has caught the attention of experts in BMT from around the country and she was recently awarded a “best abstract” prize from the American Society of Blood and Marrow Transplantation in recognition of her scientific contributions in this area. As a member of the Blood and Marrow Transplantation Program at the University of Michigan, she is working to lower the incidence of acute GVHD and ultimately improve upon survival and quality of life following allogeneic HCT. Recent Publications:
- Choi SW, Levine JE, Ferrara JLM. Pathogenesis and management of graft-versus-host disease. Immunol Allergy Clin North Am, 30: 75-101, 2010.
- Choi SW, Levine J. Indications for hematopoietic cell transplantation for children with severe congenital neutropenia. Pediatr Transplant, 14: 937-9, 2010.
- Choi S, Reddy P. HDAC inhibition and graft versus host disease. Mol Med, 17: 404-16, 2011.
- Choi, SW, Stiff P, Cooke K, Ferrara JLM, Braun T, Kitko C, Reddy P, Yanik G, Mineishi S, Paczesny S, Hanauer D, Pawarode A, Peres E, Rodriguez T, Smith S, Levine JE. TNF-inhibition with etanercept for graft versus host disease prevention in high risk HCT: Lower TNFR1 levels correlate with better outcomes. Biol Blood Marrow Transplant, 18:1525-32, 2012.
- Choi SW, Chang L, Hanauer DA, Shaffer-Hartman J, Teitelbaum D, Lewis I, Blackwood A, Akcasu N, Steel J, Christensen J, Niedner MF. Rapid reduction of central line infections in hospitalized pediatric oncology patients through simple quality improvement methods. Pediatr Blood Cancer, ePub Ahead of Print, doi: 10.1002/pbc.24187, 2012.
Dr. Sung Choi, who was raised in Southeastern Michigan, received her B.S. in Biology from the University of Michigan, M.D. from Wayne State University, and M.S. in Clinical Research Design and Statistical Analysis from the University of Michigan. She completed her pediatric residency at New York University and then returned to her home state for fellowship training in pediatric hematology-oncology at the University of Michigan. She then joined the Department of Pediatrics and Communicable Diseases in 2006 as a faculty member in the Blood and Marrow Transplantation Program. She and her husband, David Hanauer, who is also on faculty in the Department of Pediatrics, have three young children and enjoy keeping them busy with activities around Ann Arbor.