David Paul Olson MD

Assistant Professor, Pediatrics
Specialties: 
Pediatric Endocrinology, Pediatrics
Clinical Interests:

Obesity and diabetes

Locations

U of M Pediatric Endocrinology & Metabolism

C.S. Mott Children's Hospital
1540 E. Hospital Dr., Level 8, Reception B
Ann Arbor
MI
48109
Phone:
734-764-5175

U of M Pediatric Multispecialty Clinic - Endocrinology

C.S Mott Children's Hospital Floor 8 Medical Subspecialty Clinic
1540 E Hospital Dr SPC 4259
Ann Arbor
MI
48109
Phone:
734-936-4185
Fax:
734-615-3353

U of M Pediatric Endocrinology

Northville Health Center
39901 Traditions Dr Ste 240
Northville
MI
48168
Phone:
734-764-5175

Credentials

Medical School or Training

  • University of Michigan Medical School, 1999

Fellowship

  • Pediatric Endocrinology, Children's Hospital of Boston, 2005

Professional Organizations

  • Pediatric Endocrine Society

Board Certification

  • Pediatric Endocrinology

Research

Using novel mouse models, we are exploring the neuroanatomic and molecular pathways used by the brain to regulate metabolism and energy homeostasis. We are focused on dissecting the physiologic functions of subsets of neurons within the paraventricular nucleus of the hypothalamus, a critical brain region for body weight regulation. We take advantage of both novel mouse models and viral expression systems to manipulate neural activity and gene expression in specific neuronal populations in the brain in order to understand their role in physiology. Additional studies with collaborators at the Beth Israel Deaconess Medical Center, Boston, are using inducible, neuron-specific genetic changes to clarify the molecular basis of daily, biologic rhythms and explore how disruption of these rhythms predisposes organisms (rodents and humans) to pathologic changes in metabolism.

Biography

David Olson earned his M.D. and Ph.D. at the University of Michigan (the latter in Cellular and Molecular Biology). He served his internship and residency at Children’s Hospital Boston, followed by a fellowship in pediatric endocrinology and metabolism at Children’s Hospital Boston/Joslin Diabetes Center. Prior to returning to the University of Michigan, Dr. Olson was on staff at Children's Hospital Boston and affiliated with the Department of Newborn Medicine at Brigham and Women’s Hospital. His postdoctoral research was performed at Beth Israel Deaconess Medical Center, Division of Endocrinology.

Using novel mouse models, Dr. Olson is exploring gene expression changes in specific neuronal populations in the brain that are known to be important in regulating energy balance; these studies are directed at examining the link between gene expression in specific areas of the brain and altered metabolism. Additional studies using neuron-specific genetic changes are underway to clarify the molecular basis of daily biologic rhythms and explore how disruption of these rhythms predisposes organisms (rodents and humans) to pathologic changes in metabolism.

Links